Hexarelin
A potent synthetic ghrelin receptor agonist that produces one of the strongest GH pulses among the GHRP family.
Overview
Hexarelin is a 6-amino-acid GHRP closely related to GHRP-6 but more potent and longer-acting. It produces large GH pulses but is less selective than newer peptides like Ipamorelin and may elevate cortisol or prolactin meaningfully.
Benefits
- Strong GH release per dose
- Potential cardioprotective effects in animal research
- Supports lean tissue building
Mechanism of Action
Activates the ghrelin receptor (GHS-R1a) in the pituitary and hypothalamus to drive growth hormone release, while also engaging non-GHS-R cardiac receptors.
Dosage (informational only)
- Typical range
- 100–200 mcg per dose
- Frequency
- 1–3x daily
Desensitization can occur with chronic use. Cycle protocols are common.
Side Effects
- Cortisol and prolactin elevation
- Water retention
- Receptor desensitization with chronic use
Related peptides
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