Selank
A synthetic peptide modeled on tuftsin, used in Russia for anxiety and cognitive enhancement without the sedation of typical anxiolytics.
Overview
Selank is a heptapeptide derived from human tuftsin with chemical modifications that extend its activity. Developed in Russia, it's primarily used as an anxiolytic but also shows nootropic effects without sedation, dependence, or memory impairment.
Benefits
- Reduces anxiety without sedation
- May improve memory and focus
- Modulates BDNF and GABA pathways
- No reported dependence in research
Mechanism of Action
Acts on multiple systems including GABA receptors, neurotrophic factors (BDNF, NGF), and immune modulation, producing anxiolytic and pro-cognitive effects.
Dosage (informational only)
- Typical range
- 250–900 mcg per day
- Frequency
- 1–3x daily, intranasally
Most commonly used as an intranasal spray. Cycling may help maintain sensitivity.
Side Effects
- Generally well-tolerated
- Possible nasal irritation
- Mild headache in some users
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