GHK-Cu (Copper Peptide)

GHK-Cu is a small copper-binding peptide naturally present in human plasma at levels that decline with age. It has decades of dermatological research behind it and has become one of the fastest-growing peptides in skincare, hair restoration, and longevity-focused biohacking.

• Stimulates collagen and elastin production
• Supports skin firmness and wound healing
• May promote hair follicle activity
• Antioxidant and anti-inflammatory effects

GHK-Cu binds copper ions and acts as a signaling molecule that activates wound repair pathways, modulates gene expression toward a younger phenotype, and supports antioxidant defense systems in the skin.

Typical range

1–3 mg subcutaneous; 2% topical concentration

Frequency

Daily (topical) or 2–3x weekly (subcutaneous)

Topical formulations are most common for cosmetic use. Subcutaneous protocols are more experimental.

• Generally well-tolerated topically
• Possible mild redness or irritation
• Rare allergic reactions