Thymosin Beta-4 (full-length)
The full 43-amino-acid Thymosin Beta-4 protein — the natural parent molecule that the popular synthetic TB-500 fragment was derived from.
Overview
Thymosin Beta-4 (Tβ4) is the most abundant member of the beta-thymosin family in mammalian tissue. While TB-500 is a synthetic fragment of this molecule, full-length Tβ4 is the natural form and has been investigated in clinical trials for cardiac repair, neurological recovery, and corneal wound healing.
Benefits
- Promotes cell migration and angiogenesis
- Supports cardiac repair after injury
- Studied for neurological recovery and corneal wound healing
- Modulates inflammation and stem cell recruitment
Mechanism of Action
Sequesters monomeric actin to regulate cytoskeletal dynamics and cell migration. Also recruits progenitor cells to sites of tissue damage and modulates inflammatory signaling.
Dosage (informational only)
- Typical range
- 1–5 mg per dose in research protocols
- Frequency
- Varies by protocol
Distinct from TB-500 (the synthetic 17-mer fragment) — this is the full 43-amino-acid molecule.
Side Effects
- Generally well-tolerated in trials
- Possible injection site reactions
- Limited large human safety data
Related peptides
A pentadecapeptide derived from a gastric protein, widely studied for its regenerative and cytoprotective effects.
A synthetic fragment of Thymosin Beta-4 widely used in injury recovery research and frequently stacked with BPC-157.
A naturally occurring thymic peptide used clinically as an immunomodulator for chronic viral infections and immune support.