KPV Peptide
A short tripeptide fragment of α-MSH studied for anti-inflammatory effects in the gut and skin without pigmentation effects.
Overview
KPV (lysine-proline-valine) is the C-terminal tripeptide of α-MSH. It retains the anti-inflammatory properties of the parent hormone without affecting pigmentation — and has been studied for inflammatory bowel disease, eczema, and other inflammation-driven conditions.
Benefits
- Anti-inflammatory in gut and skin
- Studied for IBD applications
- May reduce systemic inflammation
- Some oral bioavailability
Mechanism of Action
Modulates inflammatory cytokine production via melanocortin pathways without engaging MC1R-driven pigmentation.
Dosage (informational only)
- Typical range
- 200–500 mcg per day
- Frequency
- Once or twice daily
Available in oral, subcutaneous, and topical forms depending on the target tissue.
Side Effects
- Generally well-tolerated in studies
- Limited large-scale human data
- Possible local irritation with topical use
Related peptides
A pentadecapeptide derived from a gastric protein, widely studied for its regenerative and cytoprotective effects.
A synthetic fragment of Thymosin Beta-4 widely used in injury recovery research and frequently stacked with BPC-157.
A naturally occurring thymic peptide used clinically as an immunomodulator for chronic viral infections and immune support.